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Platelet-activating factor receptor : ウィキペディア英語版 | Platelet-activating factor receptor
The platelet-activating factor receptor is a G-protein coupled receptor which binds platelet-activating factor.
(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5724 )〕 Its pathogenetic role in chronic kidney failure has also been reported recently. 〔cite journal | author = Correa-Costa M | title = Activation of platelet-activating factor receptor exacerbates renal inflammation and promotes fibrosis. | journal = Lab Invest. | volume = 94 | issue = 4 |date=Apr 2014 | pmid = 24492283 | url = http://www.nature.com/labinvest/journal/v94/n4/full/labinvest2013155a.html | pages = 455-466 | doi=10.1038/labinvest.2013.155}}〕 ==Ligands== Agonists * Platelet activating factor Antagonists * Israpafant (Y-24180) * WEB 2086 }}
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